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KMID : 0614620080520010042
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Korean Journal of Gastroenterology
2008 Volume.52 No. 1 p.42 ~ p.47
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A Case of Carcinosarcoma in a Patient with Corrosive Esophagitis
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Oak Ju-Hyun
Cho Kyu-Do
Paik Chang-Nyol
Chung Woo-Chul
Lee Kang-Moon
Kim Jin-Dong
Jung Ji-Han
Lee Jeong-Rok
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Abstract
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Carcinosarcoma of the esophagus is a rare malignancy accounting for approximately 1-2% of all esophageal neoplasms. It presents as a bulky intraluminal polypoid lesion mainly in the mid to lower esophagus, which harbors both carcinomatous and sarcomatous components histologically. It often presents relatively early because of its rapid intraluminal growth. We report the case of a 69-year-old man who had suffered from dysphagia for 1 month. He was previously admitted to the hospital due to corrosive esophagitis caused by ingestion of acetic acid. Endoscopy and radiological studies revealed a bulky polypoid mass with superficial ulcerations and mucosal friability, measuring 10 cm in length approximately, in the mid-esophagus. Subtotal esophagectomy with esophagogastrostomy was done. Microscopically it was composed of sarcomatous component intermingled with squamous cell carcinoma. Immunohistochemical stains reveal cytokeratin, 34βE12, and p63 positivity in the nests of carcinoma, and desmin and vimentin positivity in the spindle cells of sarcomatous stoma. (Korean J Gastroenterol 2008;52:42-47)
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KEYWORD
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Carcinosarcoma, Esophagus, Corrosiveesophagitis
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